Sonia Núñez-Vázquez Selected Research

Prohibitins

12/2023	The prohibitin-binding compound fluorizoline induces the pro-inflammatory cytokines interleukin-8 and interleukin-6 through the activation of JNK and p38 MAP kinases.
9/2021	The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells.
1/2021	NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4.
10/2020	The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells.
1/2017	The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax.
10/2016	Targeting prohibitins induces apoptosis in acute myeloid leukemia cells.

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Sonia Núñez-Vázquez Research Topics

Disease

2	Neoplasms (Cancer) 12/2023 - 09/2021
2	Hematologic Neoplasms (Hematological Malignancy) 12/2023 - 09/2021
1	Lung Neoplasms (Lung Cancer) 09/2021
1	Leukemia 01/2021
1	Multiple Myeloma 10/2020
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2017
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2017
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2016

Drug/Important Bio-Agent (IBA)

6	ProhibitinsIBA 12/2023 - 10/2016
1	rocaglamideIBA 09/2021
1	Carbonyl Cyanide m-Chlorophenyl Hydrazone (CCCP)IBA 09/2021
1	venetoclaxIBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	ibrutinibIBA 01/2017
1	acadesineIBA 01/2017